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Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
University of California, Davis Nancy Lane Disease Team Therapy Planning I Increasing the endogenous mesenchymal stem cells to the bone surface to treat osteoporosis $110,000
The J. David Gladstone Institutes Deepak Srivastava Basic Biology III Mechanisms of Direct Cardiac Reprogramming $1,708,560
Scripps Research Institute James Williamson Creativity Awards Stem Cell Summer Academy: Creating the Next Generation of Scientists $206,250
University of California, Berkeley Zhigang He Research Leadership 7 Developing a regeneration-based functional restoration treatment for spinal cord injury $5,609,890
The J. David Gladstone Institutes Deepak Srivastava Early Translational III Direct Cardiac Reprogramming for Heart Regeneration $6,319,110
University of California, San Francisco Tippi MacKenzie New Faculty Physician Scientist In Utero Embryonic Stem Cell Transplantation to Treat Congenital Anomalies $2,661,742
Cedars-Sinai Medical Center Dan Gazit Disease Team Therapy Planning I Genetically Engineered Mesenchymal Stem Cells for the Treatment of Vertebral Compression Fractures. $109,743
University of California, San Francisco Katherine Nielsen Creativity Awards [REDACTED] SEP High School Intern Program $143,550
Stanford University Helen Blau Early Translational III Local Delivery of Rejuvenated Old Muscle Stem Cells to Increase Strength in Aged Patients $1,825,920
Cedars-Sinai Medical Center Robert Baloh New Faculty Physician Scientist Human iPSC modeling and therapeutics for degenerative peripheral nerve disease $3,031,737
Geron Corporation Jane Lebkowski Targeted Clinical Development Evaluation of Safety and Preliminary Efficacy of Escalating Doses of GRNOPC1 in Subacute Spinal Cord Injury $24,846,856
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Planning I Stem Cells Secreting GDNF for the Treatment of ALS $89,834
Stanford University Sean Wu Basic Biology III Elucidating Molecular Basis of Hypertrophic Cardiomyopathy with Human Induced Pluripotent Stem Cells $1,425,600
Stanford University Michael Longaker Traning Grant I-1 Stanford CIRM Training Program $3,733,707
University of California, San Diego Mark Tuszynski Early Translational III Functional Neural Relay Formation by Human Neural Stem Cell Grafting in Spinal Cord Injury $4,699,569
Beckman Research Institute of City of Hope Jiing-Kuan Yee Basic Biology III Use of human iPS cells to study spinal muscular atrophy $1,268,868
Stanford University Robert Robbins Disease Team Therapy Planning I Human Embryonic Stem Cell-Derived Cardiomyocytes for Patients with End Stage Heart Failure $108,895
University of California, San Diego Deborah Spector Basic Biology III Viral-host interactions affecting neural differentiation of human progenitors $1,372,660
University of California, San Francisco Susan Fisher Traning Grant I-1 Training Grant I $3,620,652
Stanford University Renee Reijo Pera Early Translational III Autologous iPSC Therapy for Urinary Incontinence $5,279,607
University of California, Berkeley Song Li Basic Biology III Induced Pluripotent Stem Cells for Tissue Regeneration $1,341,064
University of California, Davis Vicki Wheelock Disease Team Therapy Planning I MSC engineered to produce BDNF for the treatment of Huntington's disease $99,248
The Parkinson's Institute R. Jeremy Nichols Basic Biology III Understanding the role of LRRK2 in iPSC cell models of Parkinson's Disease $1,482,822
University of California, San Diego Yang Xu Early Translational III Human ES cell based therapy of heart failure without allogenic immune rejection $1,857,600
University of California, Los Angeles Ali Nsair Basic Biology III Characterization and Engineering of the Cardiac Stem Cell Niche $1,181,306
StemCells, Inc. Alexandra Capela Disease Team Therapy Planning I Neuroprotection to treat Alzheimer's: a new paradigm using human central nervous system cells $98,050
Stanford University Renee Reijo Pera Basic Biology III Correlated time-lapse imaging and single cell molecular analysis of human embryo development $1,425,600
University of Southern California Robert Maxson Traning Grant I-1 CIRM Stem Cell Biology Training Grant $3,158,532
University of California, San Diego Eugene Yeo Early Translational III Molecules to Correct Aberrant RNA Signature in Human Diseased Neurons $1,654,830
California Polytechnic State University, San Luis Obispo Trevor Cardinal Bridges Masters of Science Specialization in Stem Cell Technology $3,020,182
University of California, San Diego Anirvan Ghosh Basic Biology III Investigation of synaptic defects in autism using patient-derived induced pluripotent stem cells $1,391,400
University of California, Los Angeles Stanley Nelson Disease Team Therapy Planning I Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $86,414
Stanford University Michael Clarke Basic Biology III USP16 controls stem cell number: implications for Down Syndrome $1,425,600
University of California, Los Angeles Owen Witte Traning Grant I-1 CIRM Type I Comprehensive Training Program $3,750,000
University of California, San Francisco Arnold Kriegstein Early Translational III Human ES cell-derived MGE inhibitory interneuron transplantation for spinal cord injury $1,623,251
California State Polytechnic University, Pomona Jill Adler-Moore Bridges Collaborative CIRM Bridges Program to Enhance Stem Cell Research Training and Education $3,008,975
Stanford University Michele Calos Early Translational II Stem Cell Therapy for Duchenne Muscular Dystrophy $2,325,933
University of California, Santa Cruz Bin Chen New Faculty I Molecular mechanisms of neural stem cell differentiation in the developing brain $2,200,715
University of California, Irvine leif Havton Early Translational II Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $1,614,441
University of California, Davis Jan Nolta Early Translational I Sustained siRNA production from human MSC to treat Huntingtons Disease and other neurodegenerative disorders $2,753,559
Stanford University Sarah Heilshorn Tools and Technologies II Preparation and Delivery of Clinically Relevant Numbers of Stem Cells Using 3D Hydrogels $1,415,981
Stanford University Karl Deisseroth New Faculty I Bioengineering technology for fast optical control of differentiation and function in stem cells and stem cell progeny $3,154,719
The Salk Institute for Biological Studies Fred Gage Early Translational II Crosstalk: Inflammation in Parkinson’s disease (PD) in a humanized in vitro model $2,472,839
The Parkinson's Institute J. William Langston Tools and Technologies II Editing of Parkinson’s disease mutation in patient-derived iPSCs by zinc-finger nucleases $1,327,983
University of California, Los Angeles Kathrin Plath New Faculty I In vitro reprogramming of mouse and human somatic cells to an embryonic state $2,229,427
University of California, San Francisco Arturo Alvarez-Buylla Early Translational II Inhibitory Nerve Cell Precursors: Dosing, Safety and Efficacy $1,752,058
Cedars-Sinai Medical Center Clive Svendsen Tools and Technologies II Use of iPS cells (iPSCs) to develop novels tools for the treatment of spinal muscular atrophy. $1,933,022
University of Southern California Songtao Shi New Faculty I Oral and Craniofacial Reconstruction Using Mesenchymal Stem Cells $3,428,464
University of California, Irvine Brian Cummings Early Translational II Neural restricted, FAC-sorted, human neural stem cells to treat traumatic brain injury $1,708,549
Stanford University Ricardo Dolmetsch Tools and Technologies II Development of small molecule screens for autism using patient-derived iPS cells $1,884,808
Beckman Research Institute of City of Hope Tiziano Barberi New Faculty I Skeletal muscle development from hESC and its in vivo applications in animal models of muscular dystrophy $1,623,064
Beckman Research Institute of City of Hope Yanhong Shi Early Translational II Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,731,750
Stanford University Marius Wernig Tools and Technologies II Cellular tools to study brain diseases affecting synaptic transmission $1,906,494
Buck Institute for Age Research Xianmin Zeng Early Translational II Banking transplant ready dopaminergic neurons using a scalable process $6,016,624
University of California, Los Angeles Stanley Carmichael Tools and Technologies II Development of a Hydrogel Matrix for Stem Cell Growth and Neural Repair after Stroke $1,825,613
University of California, Davis Chong-Xian Pan New Faculty I Combinatorial Chemistry Approaches to Develop LIgands against Leukemia Stem Cells $2,567,397
University of California, Davis Mark Zern Early Translational II Liver Cell Transplantation $5,199,767
University of California, San Diego David Traver New Faculty I Genetic dissection of mesodermal commitment to the hematopoietic fates. $2,185,369
University of California, Los Angeles Noriyuki Kasahara Early Translational II Stem cell-based carriers for RCR vector delivery to glioblastoma $3,370,607
Fluidigm Corporation Marc Unger Tools and Technologies II Development and Application of Versatile, Automated, Microfluidic Cell Culture System $1,943,904
The Salk Institute for Biological Studies Lei Wang New Faculty I Genetic Encoding Novel Amino Acids in Embryonic Stem Cells for Molecular Understanding of Differentiation to Dopamine Neurons $2,626,937
University of California, San Diego Catriona Jamieson Early Translational II Preclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy $3,341,758
Stanford University Michele Calos Tools and Technologies II Site-specific integration of Lmx1a, FoxA2, & Otx2 to optimize dopaminergic differentiation $1,619,627
University of California, Los Angeles Siavash Kurdistani New Faculty I Epigenetics in cancer stem cell initiation and clinical outcome prediction $3,238,450
University of California, Irvine Leslie Thompson Early Translational II A hESc-based Development Candidate for Huntington's Disease $3,799,817
University of California, San Diego Shu Chien Tools and Technologies II Development of Synthetic Microenvironments for Stem Cell Growth and Differentiation $1,832,515
University of California, Los Angeles Hanna Mikkola New Faculty I Mechanisms of Hematopoietic stem cell Specification and Self-Renewal $2,286,900
University of California, San Diego Alysson Muotri Early Translational II Developing a drug-screening system for Autism Spectrum Disorders using human neurons $1,491,471
University of California, Berkeley Steven Conolly Tools and Technologies II Magnetic Particle Imaging: A Novel Ultra-sensitive Imaging Scanner for Tracking Stem Cells In Vivo $1,452,360
University of California, San Diego David Cheresh Basic Biology III Molecular basis of human ES cell neurovascular differentiation and co-patterning $1,361,448
University of Southern California Mohammad Pashmforoush New Faculty I Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors $3,149,806
Beckman Research Institute of City of Hope David DiGiusto Early Translational II Development of RNA-based approaches to stem cell gene therapy for HIV $3,124,130
University of California, Irvine Andrew Putnam New Faculty I A Novel Engineered Niche to Explore the Vasculogenic Potential of Embryonic Stem Cells $2,108,683
The Salk Institute for Biological Studies Inder Verma Early Translational I Curing Hematological Diseases $6,649,347
University of California, Los Angeles Sophie Deng Early Translational II Regeneration of Functional Human Corneal Epithelial Progenitor Cells $1,654,058
GMR Epigenetics Jifan Hu Tools and Technologies II Robust generation of induced pluripotent stem cells by a potent set of engineered factors $1,452,693
Sanford-Burnham Medical Research Institute Evan Snyder Early Translational I Developmental Candidates for Cell-Based Therapies for Parkinson's Disease (PD) $5,416,003
University of California, Irvine Henry Klassen Early Translational II Human retinal progenitor cells as candidate therapy for retinitis pigmentosa $4,738,251
University of California, Berkeley David Schaffer Tools and Technologies II Engineering Defined and Scaleable Systems for Dopaminergic Neuron Differentiation of hPSCs $1,493,928
University of California, Davis Alice Tarantal Early Translational I In Utero Model to Assess the Fate of Transplanted Human Cells for Translational Research and Pediatric Therapies $4,214,592
Scripps Research Institute Peter Schultz Early Translational II Cartilage Regeneration by the Chondrogenic Small Molecule PRO1 during Osteoarthritis $6,792,660
Stanford University Howard Chang New Faculty I Noncoding RNAs in Cell Fate Determination $3,203,926
University of California, Los Angeles Martin Martin Tools and Technologies II Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
University of California, San Diego Eugene Yeo Basic Biology III Neural and general splicing factors control self-renewal, neural survival and differentiation $1,372,660
BioTime, Inc. Michael West Early Translational I Addressing the Cell Purity and Identity Bottleneck Through Generation and Expansion of Clonal Human Embryonic Progenitor Cell Lines $4,721,706
iPierian, Inc. John Dimos Early Translational II New Drug Discovery for SMA using Patient-derived Induced Pluripotent Stem Cells $5,665,887
University of California, Los Angeles Gay Crooks Basic Biology III Forming the Hematopoietic Niche from Human Pluripotent Stem Cells $1,375,983
Sanford-Burnham Medical Research Institute Robert Wechsler-Reya Research Leadership 1 The role of neural stem cells in cerebellar development, regeneration and tumorigenesis $5,919,616
University of California, Davis Roslyn Isseroff Early Translational II Bone Marrow Mesenchymal Stem Cells to Heal Chronic Diabetic Wounds $4,526,900
University of California, Merced Jennifer Manilay New Faculty I Enhancing Survival of Embryonic Stem Cell-Derived Grafts by Induction of Immunological Tolerance $1,581,056
University of California, Santa Barbara Peter Coffey Research Leadership 2 Development of Cellular Therapies for Retinal Disease $4,880,116
Gamma Medica-Ideas, Inc. James Hugg Tools and Technologies II Tri-resolution Visualization System for Stem Cells and Tissue Regeneration Monitoring $1,528,599
Children's Hospital of Los Angeles Markus Muschen Early Translational II Dual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication $3,607,305
Stanford University Joanna Wysocka New Faculty I Trithorax and Polycomb methyltransferase complexes in cell fate determination. $2,374,020
Stanford University Brian Rutt Tools and Technologies II Development of Single Cell MRI Technology using Genetically-Encoded Iron-Based Reporters $1,930,608
University of California, Los Angeles Bruno Peault Early Translational II Harnessing native fat-residing stem cells for bone regeneration $5,391,560
Scripps Research Institute Kristin Baldwin New Faculty I Generating pluripotent cell lines from neurons. $2,803,375
University of California, Los Angeles Dana Jones New Faculty I Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity $2,675,234
Cedars-Sinai Medical Center Dan Gazit Early Translational II Systemic Adult Stem Cell Therapy for Osteoporosis-Related Vertebral Compression Fractures $1,927,698
University of California, San Francisco Mark Anderson Transplantation Immunology Stem cell differentiation to thymic epithelium for inducing tolerance to stem cells $1,314,090
Total:
$275,779,734.00

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