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Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology IV Studying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells $1,582,606
University of California, San Francisco Jeremy Reiter Basic Biology IV Modeling disease in human embryonic stem cells using new genetic tools $1,387,800
Stanford University Howard Chang Basic Biology IV Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
Stanford University Alexander Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,064,224
The J. David Gladstone Institutes Steven Finkbeiner Basic Biology IV Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,506,420
University of California, San Diego George Sen Basic Biology IV Regulation of Epidermal Self-Renewal and Differentiation by Histone and DNA Demethylases. $1,080,000
The J. David Gladstone Institutes Benoit Bruneau Basic Biology IV Epigenetic regulation of human cardiac differentiation $1,708,560
University of California, Los Angeles Kathrin Plath Basic Biology IV Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
University of California, San Diego Miles Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
The J. David Gladstone Institutes Sheng Ding Basic Biology IV A new paradigm of lineage-specific reprogramming $1,708,560
Stanford University Ben Barres Basic Biology IV Phenotyping Human Astrocytes in Health and Disease $1,385,517
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,382,400
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
Stanford University Roel Nusse Basic Biology IV Asymmetric stem cell division oriented by a local self-renewing signal $1,195,811
Cedars-Sinai Medical Center Eduardo Marbán Basic Biology IV Mechanism of heart regeneration by cardiosphere-derived cells $1,367,604
University of California, San Diego Eugene Yeo Basic Biology IV Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,393,200
University of California, San Francisco Barbara Panning Basic Biology IV Investigation of the role of O-GlcNAcylation in SOX2 function during reprogramming $1,285,214
University of California, Berkeley Robert Tjian Basic Biology IV Transcriptional regulation of pluripotency in human embryonic stem cells $1,220,968
Stanford University Anne Brunet Basic Biology IV Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
University of California, San Francisco Heike Daldrup-Link SEED Grant Labeling of human embryonic stem cells with iron oxide nanoparticles and fluorescent dyes for a non-invasive cell depiction with MR imaging and optical imaging $251,088
Sanford-Burnham Medical Research Institute Zhuohua Zhang SEED Grant Modeling Parkinson's Disease Using Human Embryonic Stem Cells $758,999
University of California, Los Angeles Hanna Mikkola SEED Grant Improving microenvironments to promote hematopoietic stem cell development from human embryonic stem cells $577,037
Stanford University Kenneth Weinberg SEED Grant Embryonic stem cell-derived thymic epithelial cells $658,057
Beckman Research Institute of City of Hope Timothy O'Connor SEED Grant Sources of Genetic Instability in Human Embryonic Stem Cells. $357,978
Stanford University Joseph Wu SEED Grant In Vivo Imaging of Human Embryonic Stem Cell Derivatives and Tumorigenicity $658,123
University of California, San Francisco Miguel Ramalho-Santos SEED Grant Transcriptional Regulation of Human Embryonic Stem Cells $618,901
Stanford University Joanna Wysocka SEED Grant Role of Chromatin Modifiers in Regulating Human Embryonic Stem Cell Pluripotency $658,126
Stanford University Phillip Yang SEED Grant In Vivo Molecular Magnetic Resonance Imaging of Human Embryonic Stem Cells in Murine Model of Myocardial Infarction $658,125
University of California, San Diego Binhai Zheng SEED Grant Genetic manipulation of human embryonic stem cells and its application in studying CNS development and repair $642,361
University of California, San Francisco Thea Tlsty SEED Grant Role of the tumor suppressor gene, p16INK4a, in regulating stem cell phenotypes in embryonic stem cells and human epithelial cells. $639,150
University of California, Berkeley Carolyn Bertozzi SEED Grant Profiling surface glycans and glycoprotein expression of human embryonic stem cells $498,409
University of California, San Francisco Valerie Weaver SEED Grant Force, Dimensionality and Stem Cell Fate $561,082
University of California, Irvine Brian Cummings SEED Grant The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $619,223
University of California, Riverside Frank Sauer SEED Grant Non-coding RNA as tool for the active control of stem cell differentiation $595,469
Sanford-Burnham Medical Research Institute Alexey Terskikh SEED Grant Analysis of Candidate Neural Crest Cells Derived from Human ES Cells $759,000
University of California, San Francisco Holger Willenbring SEED Grant Induction of pluripotency in fibroblasts by fusion with enucleated human embryonic stem cell syncytia $342,962
University of Southern California Qilong Ying SEED Grant Self-renewal of human embryonic stem cells $663,209
Stanford University Aaron Hsueh SEED Grant Patient-specific cells with nuclear transfer $656,074
University of California, Davis Ebenezer Yamoah SEED Grant Hair Cells and Spiral Ganglion Neuron Differentiation from Human Embryonic Stem Cells $469,327
University of Southern California Peter Laird SEED Grant Screening for Oncogenic Epigenetic Alterations in Human ES Cells $685,000
University of California, Irvine Charles Limoli SEED Grant Using human embryonic stem cells to treat radiation-induced stem cell loss: Benefits vs cancer risk $625,617
University of California, Irvine Vincent Procaccio SEED Grant Mitochondrial Dysfunction in Embryonic Stem Cells $632,500
University of California, Irvine Kyoko Yokomori SEED Grant Derivation and characterization of human ES cells from FSHD embryos $632,500
University of California, Irvine Thomas Lane SEED Grant Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination $425,594
University of California, Davis A. Reddi SEED Grant hESCs for Articular Cartilage Regeneration $367,650
University of California, Irvine Grant MacGregor SEED Grant Production of Oocytes from Human ES Cells $623,781
The J. David Gladstone Institutes Fen-Biao Gao SEED Grant MicroRNAs in Human Stem Cell Differentiation and Mental Disorders $791,000
University of California, Los Angeles Noriyuki Kasahara SEED Grant Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $469,219
University of California, Los Angeles Michael Teitell SEED Grant Role of Mitochondria in Self-Renewal Versus Differentiation of Human Embryonic Stem Cells $635,024
Ludwig Institute for Cancer Research Bing Ren SEED Grant Mapping the transcriptional regulatory elements in the genome of hESC $691,489
University of California, Berkeley Ellen Robey SEED Grant In Vitro Differentiation of T cells from Human Embryonic Stem Cells. $499,999
The J. David Gladstone Institutes Eric Verdin SEED Grant Role of HDAC in human stem cells pluripotentiality and differentiation $790,999
Stanford University Julien Sage SEED Grant Functions of RB family proteins in human embryonic stem cells $520,777
University of California, San Francisco Didier Stainier SEED Grant Endodermal differentiation of human ES cells $635,242
Scripps Research Institute Peter Schultz SEED Grant A Chemical Approach to Stem Cell Biology $784,900
University of California, San Diego Cornelis Murre SEED Grant Generation of long-term cultures of human hematopoietic multipotent progenitors from embryonic stem cells $538,211
Sanford-Burnham Medical Research Institute Robert Oshima SEED Grant Trophoblast differentiation of human ES cells. $748,240
University of California, Riverside Michael Pirrung SEED Grant Stem Cell Survival and Differentiation Through Chemical Genetics $543,987
The Salk Institute for Biological Studies Samuel Pfaff SEED Grant Gene regulatory mechanisms that control spinal neuron differentiation from hES cells. $807,749
University of California, Los Angeles Zoran Galic SEED Grant Genetic Enhancement of the Immune Response to Melanoma via hESC-derived T cells $642,501
University of Southern California Wange Lu SEED Grant Regulation of human neural progenitor cell proliferation by Ryk-mediated Wnt signaling $668,987
Children's Hospital of Los Angeles Elizabeth Lawlor SEED Grant hESC as tools to investigate the neural crest origin of Ewing's sarcoma $675,001
The J. David Gladstone Institutes Warner Greene SEED Grant The APOBEC3 Gene Family as Guardians of Genome Stability in Human Embryonic Stem Cells $777,467
University of California, Santa Cruz David Feldheim SEED Grant Assessing the role of Eph/ephrin signaling in hESC growth and differentiation $499,999
University of California, San Diego Sylvia Evans SEED Grant Specification of Ventricular Myocyte and Pacemaker Lineages Utilizing Human Embryonic Stem Cells $609,999
University of California, San Francisco Su Guo SEED Grant Identifying small molecules that stimulate the differentiation of hESCs into dopamine-producing neurons $564,309
University of California, Los Angeles William Lowry SEED Grant Modeling Human Embryonic Development with Human Embryonic Stem Cells $571,575
University of Southern California David Hinton SEED Grant Therapeutic potential of Retinal Pigment Epithelial cell lines derived from hES cells for retinal degeneration. $684,322
University of California, San Diego Anirvan Ghosh SEED Grant Generation of forebrain neurons from human embryonic stem cells $612,075
Sanford-Burnham Medical Research Institute Ziwei Huang SEED Grant New Chemokine-Derived Therapeutics Targeting Stem Cell Migration $759,000
University of California, Irvine Michelle Khine SEED Grant Micro Platform for Controlled Cardiac Myocyte Differentiation $363,707
University of California, San Diego Catriona Jamieson SEED Grant Derivation and Characterization of Cancer Stem Cells from Human ES Cells $642,500
Stanford University Krishna Shenoy SEED Grant Technology for hESC-Derived Cardiomyocyte Differentiation and Optimization of Graft-Host Integration in Adult Myocardium $634,287
Sanford-Burnham Medical Research Institute Hudson Freeze SEED Grant Role of Glycans in Human Embryonic Stem Cell Conversion to Neural Precursor Cells $759,000
Stanford University Mark Kay SEED Grant Novel vectors for gene transfer into human ES cells $640,642
Stanford University Calvin Kuo SEED Grant Differentiation of Human Embryonic Stem Cells to Intestinal Fates $578,943
Stanford University Susan McConnell SEED Grant Optimization of guidance response in human embryonic stem cell derived midbrain dopaminergic neurons in development and disease $633,170
University of California, Irvine Frank LaFerla SEED Grant Development of human ES cell lines as a model system for Alzheimer disease drug discovery $492,750
University of California, Los Angeles Siavash Kurdistani SEED Grant Cellular epigenetic diversity as a blueprint for defining the identity and functional potential of human embryonic stem cells $641,047
University of California, San Francisco Linda Giudice SEED Grant Human Embryonic Stem Cell Differentiation to Trophoblast: Basic Biology and Clinical Translation to Improve Human Fertility $640,399
The Salk Institute for Biological Studies Senyon Choe SEED Grant A method to maintain and propagate pluripotent human ES cells $796,348
Sanford-Burnham Medical Research Institute Huei-sheng Chen SEED Grant Development of Neuro-Coupled Human Embryonic Stem Cell-Derived Cardiac Pacemaker Cells. $744,639
Sanford-Burnham Medical Research Institute Gregg Duester SEED Grant Retinoic Acid-FGF Antagonism during Motor Neuron Differentiation of Human ES Cells $759,000
Stanford University John Cooke SEED Grant EC regeneration in cerebrovascular ischemia: role of NO $658,125
University of California, Santa Cruz Bin Chen SEED Grant In vitro differentiation of hESCs into corticospinal motor neurons $500,000
University of California, Los Angeles Irvin Chen SEED Grant Genetic modification of the human genome to resist HIV-1 infection and/or disease progression $642,652
University of California, San Francisco Robert Blelloch SEED Grant MicroRNA Regulation of Human Embryonic Stem Cell Self-Renewal and Differentiation $631,831
Buck Institute for Age Research Dale Bredesen SEED Grant Programmed Cell Death Pathways Activated in Embryonic Stem Cells $734,202
Human BioMolecular Research Institute John Cashman SEED Grant Discovering Potent Molecules with Human ESCs to Treat Heart Disease $714,654
University of California, San Diego Shu Chien SEED Grant Combinatorial Platform for Optimizing Microenvironments to Control hESC Fate $638,140
University of Southern California Wange Lu Basic Biology I Defining the molecular mechanisms of somatic cell reprogramming $1,468,360
University of California, Los Angeles Luisa Iruela-Arispe Basic Biology I Molecular Characterization and Functional Exploration of Hemogenic Endothelium $1,371,477
University of California, Los Angeles Bennett Novitch Basic Biology I Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons $1,363,262
University of Southern California Martin Pera Basic Biology I The stem cell microenvironment in the maintenance of pluripotency and reprogramming $1,440,822
University of California, Los Angeles Michael Teitell Basic Biology I Mitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer $1,323,029
Stanford University Susan McConnell Basic Biology I Identification and characterization of human ES-derived DA neuronal subtypes $1,407,076
University of California, San Diego Eugene Yeo Basic Biology I RNA Binding Protein-mediated Post-transcriptional Networks Regulating HPSC Pluripotency $1,376,802
Total:
$83,748,054.00

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