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Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
University of California, San Diego Eugene Yeo Basic Biology IV Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,393,200
Cedars-Sinai Medical Center Eduardo Marbán Basic Biology IV Mechanism of heart regeneration by cardiosphere-derived cells $1,367,604
University of California, San Francisco Barbara Panning Basic Biology IV Investigation of the role of O-GlcNAcylation in SOX2 function during reprogramming $1,285,214
University of California, Berkeley Robert Tjian Basic Biology IV Transcriptional regulation of pluripotency in human embryonic stem cells $1,220,968
Stanford University Anne Brunet Basic Biology IV Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
Stanford University Michael Cleary Basic Biology IV Prostaglandin pathway regulation of self-renwal in hematopoietic and leukemia stem cells $1,244,455
University of California, Davis Deborah Lieu Basic Biology IV Induction of Pluripotent Stem Cell-Derived Pacemaking Cells $1,334,880
Beckman Research Institute of City of Hope Yanhong Shi Basic Biology IV Modeling Alexander disease using patient-specific induced pluripotent stem cells $1,367,172
University of California, San Francisco Miguel Ramalho-Santos Basic Biology IV Genetic dissection of human cellular reprogramming to pluripotency $1,184,883
University of California, San Diego Maike Sander Basic Biology IV Deciphering transcriptional control of pancreatic beta-cell maturation in vitro $1,391,400
Buck Institute for Age Research Deepak Lamba Basic Biology IV 3D Modeling of Retina using Polymer Scaffolds for Understanding Disease Pathogenesis $1,526,319
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology IV Studying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells $1,582,606
University of California, San Francisco Jeremy Reiter Basic Biology IV Modeling disease in human embryonic stem cells using new genetic tools $1,387,800
Stanford University Howard Chang Basic Biology IV Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
Stanford University Alexander Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,064,224
The J. David Gladstone Institutes Steven Finkbeiner Basic Biology IV Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,506,420
University of California, San Diego George Sen Basic Biology IV Regulation of Epidermal Self-Renewal and Differentiation by Histone and DNA Demethylases. $1,080,000
The J. David Gladstone Institutes Benoit Bruneau Basic Biology IV Epigenetic regulation of human cardiac differentiation $1,708,560
University of California, San Diego Miles Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
University of California, Los Angeles Kathrin Plath Basic Biology IV Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
Stanford University Ben Barres Basic Biology IV Phenotyping Human Astrocytes in Health and Disease $1,385,517
The J. David Gladstone Institutes Sheng Ding Basic Biology IV A new paradigm of lineage-specific reprogramming $1,708,560
University of California, San Francisco Holger Willenbring SEED Grant Induction of pluripotency in fibroblasts by fusion with enucleated human embryonic stem cell syncytia $342,962
University of Southern California Qilong Ying SEED Grant Self-renewal of human embryonic stem cells $663,209
Stanford University Aaron Hsueh SEED Grant Patient-specific cells with nuclear transfer $656,074
University of California, Davis Ebenezer Yamoah SEED Grant Hair Cells and Spiral Ganglion Neuron Differentiation from Human Embryonic Stem Cells $469,327
University of Southern California Peter Laird SEED Grant Screening for Oncogenic Epigenetic Alterations in Human ES Cells $685,000
University of California, Irvine Thomas Lane SEED Grant Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination $425,594
University of California, Irvine Charles Limoli SEED Grant Using human embryonic stem cells to treat radiation-induced stem cell loss: Benefits vs cancer risk $625,617
University of California, Irvine Vincent Procaccio SEED Grant Mitochondrial Dysfunction in Embryonic Stem Cells $632,500
University of California, Irvine Kyoko Yokomori SEED Grant Derivation and characterization of human ES cells from FSHD embryos $632,500
University of California, Davis A. Reddi SEED Grant hESCs for Articular Cartilage Regeneration $367,650
University of California, Irvine Grant MacGregor SEED Grant Production of Oocytes from Human ES Cells $623,781
The J. David Gladstone Institutes Fen-Biao Gao SEED Grant MicroRNAs in Human Stem Cell Differentiation and Mental Disorders $791,000
University of California, Los Angeles Noriyuki Kasahara SEED Grant Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $469,219
University of California, San Francisco Heike Daldrup-Link SEED Grant Labeling of human embryonic stem cells with iron oxide nanoparticles and fluorescent dyes for a non-invasive cell depiction with MR imaging and optical imaging $251,088
Stanford University Kenneth Weinberg SEED Grant Embryonic stem cell-derived thymic epithelial cells $658,057
Sanford-Burnham Medical Research Institute Zhuohua Zhang SEED Grant Modeling Parkinson's Disease Using Human Embryonic Stem Cells $758,999
University of California, Los Angeles Hanna Mikkola SEED Grant Improving microenvironments to promote hematopoietic stem cell development from human embryonic stem cells $577,037
Stanford University Joseph Wu SEED Grant In Vivo Imaging of Human Embryonic Stem Cell Derivatives and Tumorigenicity $658,123
Beckman Research Institute of City of Hope Timothy O'Connor SEED Grant Sources of Genetic Instability in Human Embryonic Stem Cells. $357,978
Stanford University Joanna Wysocka SEED Grant Role of Chromatin Modifiers in Regulating Human Embryonic Stem Cell Pluripotency $658,126
University of California, San Francisco Miguel Ramalho-Santos SEED Grant Transcriptional Regulation of Human Embryonic Stem Cells $618,901
Stanford University Phillip Yang SEED Grant In Vivo Molecular Magnetic Resonance Imaging of Human Embryonic Stem Cells in Murine Model of Myocardial Infarction $658,125
University of California, San Diego Binhai Zheng SEED Grant Genetic manipulation of human embryonic stem cells and its application in studying CNS development and repair $642,361
University of California, San Francisco Thea Tlsty SEED Grant Role of the tumor suppressor gene, p16INK4a, in regulating stem cell phenotypes in embryonic stem cells and human epithelial cells. $639,150
University of California, Berkeley Carolyn Bertozzi SEED Grant Profiling surface glycans and glycoprotein expression of human embryonic stem cells $498,409
University of California, San Francisco Valerie Weaver SEED Grant Force, Dimensionality and Stem Cell Fate $561,082
University of California, Irvine Brian Cummings SEED Grant The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $619,223
University of California, Riverside Frank Sauer SEED Grant Non-coding RNA as tool for the active control of stem cell differentiation $595,469
Sanford-Burnham Medical Research Institute Alexey Terskikh SEED Grant Analysis of Candidate Neural Crest Cells Derived from Human ES Cells $759,000
Stanford University Julien Sage SEED Grant Functions of RB family proteins in human embryonic stem cells $520,777
University of California, San Francisco Didier Stainier SEED Grant Endodermal differentiation of human ES cells $635,242
Scripps Research Institute Peter Schultz SEED Grant A Chemical Approach to Stem Cell Biology $784,900
University of California, San Diego Cornelis Murre SEED Grant Generation of long-term cultures of human hematopoietic multipotent progenitors from embryonic stem cells $538,211
Sanford-Burnham Medical Research Institute Robert Oshima SEED Grant Trophoblast differentiation of human ES cells. $748,240
The Salk Institute for Biological Studies Samuel Pfaff SEED Grant Gene regulatory mechanisms that control spinal neuron differentiation from hES cells. $807,749
University of California, Riverside Michael Pirrung SEED Grant Stem Cell Survival and Differentiation Through Chemical Genetics $543,987
University of California, Los Angeles Michael Teitell SEED Grant Role of Mitochondria in Self-Renewal Versus Differentiation of Human Embryonic Stem Cells $635,024
Ludwig Institute for Cancer Research Bing Ren SEED Grant Mapping the transcriptional regulatory elements in the genome of hESC $691,489
University of California, Berkeley Ellen Robey SEED Grant In Vitro Differentiation of T cells from Human Embryonic Stem Cells. $499,999
The J. David Gladstone Institutes Eric Verdin SEED Grant Role of HDAC in human stem cells pluripotentiality and differentiation $790,999
Sanford-Burnham Medical Research Institute Hudson Freeze SEED Grant Role of Glycans in Human Embryonic Stem Cell Conversion to Neural Precursor Cells $759,000
Stanford University Mark Kay SEED Grant Novel vectors for gene transfer into human ES cells $640,642
Stanford University Calvin Kuo SEED Grant Differentiation of Human Embryonic Stem Cells to Intestinal Fates $578,943
Stanford University Susan McConnell SEED Grant Optimization of guidance response in human embryonic stem cell derived midbrain dopaminergic neurons in development and disease $633,170
University of California, Irvine Frank LaFerla SEED Grant Development of human ES cell lines as a model system for Alzheimer disease drug discovery $492,750
University of California, Los Angeles Siavash Kurdistani SEED Grant Cellular epigenetic diversity as a blueprint for defining the identity and functional potential of human embryonic stem cells $641,047
University of California, San Francisco Linda Giudice SEED Grant Human Embryonic Stem Cell Differentiation to Trophoblast: Basic Biology and Clinical Translation to Improve Human Fertility $640,399
University of California, Los Angeles Zoran Galic SEED Grant Genetic Enhancement of the Immune Response to Melanoma via hESC-derived T cells $642,501
University of Southern California Wange Lu SEED Grant Regulation of human neural progenitor cell proliferation by Ryk-mediated Wnt signaling $668,987
Children's Hospital of Los Angeles Elizabeth Lawlor SEED Grant hESC as tools to investigate the neural crest origin of Ewing's sarcoma $675,001
The J. David Gladstone Institutes Warner Greene SEED Grant The APOBEC3 Gene Family as Guardians of Genome Stability in Human Embryonic Stem Cells $777,467
University of California, Santa Cruz David Feldheim SEED Grant Assessing the role of Eph/ephrin signaling in hESC growth and differentiation $499,999
University of California, San Diego Sylvia Evans SEED Grant Specification of Ventricular Myocyte and Pacemaker Lineages Utilizing Human Embryonic Stem Cells $609,999
University of California, San Francisco Su Guo SEED Grant Identifying small molecules that stimulate the differentiation of hESCs into dopamine-producing neurons $564,309
University of California, Los Angeles William Lowry SEED Grant Modeling Human Embryonic Development with Human Embryonic Stem Cells $571,575
University of Southern California David Hinton SEED Grant Therapeutic potential of Retinal Pigment Epithelial cell lines derived from hES cells for retinal degeneration. $684,322
University of California, San Diego Anirvan Ghosh SEED Grant Generation of forebrain neurons from human embryonic stem cells $612,075
Sanford-Burnham Medical Research Institute Ziwei Huang SEED Grant New Chemokine-Derived Therapeutics Targeting Stem Cell Migration $759,000
University of California, Irvine Michelle Khine SEED Grant Micro Platform for Controlled Cardiac Myocyte Differentiation $363,707
University of California, San Diego Catriona Jamieson SEED Grant Derivation and Characterization of Cancer Stem Cells from Human ES Cells $642,500
Stanford University Krishna Shenoy SEED Grant Technology for hESC-Derived Cardiomyocyte Differentiation and Optimization of Graft-Host Integration in Adult Myocardium $634,287
University of California, Los Angeles Irvin Chen SEED Grant Genetic modification of the human genome to resist HIV-1 infection and/or disease progression $642,652
University of California, San Francisco Robert Blelloch SEED Grant MicroRNA Regulation of Human Embryonic Stem Cell Self-Renewal and Differentiation $631,831
Buck Institute for Age Research Dale Bredesen SEED Grant Programmed Cell Death Pathways Activated in Embryonic Stem Cells $734,202
Human BioMolecular Research Institute John Cashman SEED Grant Discovering Potent Molecules with Human ESCs to Treat Heart Disease $714,654
University of California, San Diego Shu Chien SEED Grant Combinatorial Platform for Optimizing Microenvironments to Control hESC Fate $638,140
The Salk Institute for Biological Studies Senyon Choe SEED Grant A method to maintain and propagate pluripotent human ES cells $796,348
Sanford-Burnham Medical Research Institute Huei-sheng Chen SEED Grant Development of Neuro-Coupled Human Embryonic Stem Cell-Derived Cardiac Pacemaker Cells. $744,639
Sanford-Burnham Medical Research Institute Gregg Duester SEED Grant Retinoic Acid-FGF Antagonism during Motor Neuron Differentiation of Human ES Cells $759,000
Stanford University John Cooke SEED Grant EC regeneration in cerebrovascular ischemia: role of NO $658,125
University of California, Santa Cruz Bin Chen SEED Grant In vitro differentiation of hESCs into corticospinal motor neurons $500,000
University of California, San Diego Karl Willert Basic Biology I WNT signaling and the control of cell fate decisions in human pluripotent stem cells. $1,376,802
University of California, Los Angeles Robb Maclellan Basic Biology I Human Cardiovascular Progenitors, their Niches and Control of Self-renewal and Cell Fate $1,378,076
University of California, Davis Min Zhao Basic Biology I Directing migration of human stem cells with electric fields $1,052,715
University of Southern California Wange Lu Basic Biology I Defining the molecular mechanisms of somatic cell reprogramming $1,468,360
University of California, Los Angeles Luisa Iruela-Arispe Basic Biology I Molecular Characterization and Functional Exploration of Hemogenic Endothelium $1,371,477
University of California, Los Angeles Bennett Novitch Basic Biology I Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons $1,363,262
University of Southern California Martin Pera Basic Biology I The stem cell microenvironment in the maintenance of pluripotency and reprogramming $1,440,822
Total:
$83,738,266.00

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