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Search all CIRM Grants

Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
University of California, San Francisco Linda Giudice SEED Grant Human Embryonic Stem Cell Differentiation to Trophoblast: Basic Biology and Clinical Translation to Improve Human Fertility $640,399
University of California, San Francisco Su Guo SEED Grant Identifying small molecules that stimulate the differentiation of hESCs into dopamine-producing neurons $564,309
University of Southern California David Hinton SEED Grant Therapeutic potential of Retinal Pigment Epithelial cell lines derived from hES cells for retinal degeneration. $684,322
University of California, Irvine Michelle Khine SEED Grant Micro Platform for Controlled Cardiac Myocyte Differentiation $363,707
University of Southern California Wange Lu SEED Grant Regulation of human neural progenitor cell proliferation by Ryk-mediated Wnt signaling $668,987
Children's Hospital of Los Angeles Elizabeth Lawlor SEED Grant hESC as tools to investigate the neural crest origin of Ewing's sarcoma $675,001
University of California, San Diego Sylvia Evans SEED Grant Specification of Ventricular Myocyte and Pacemaker Lineages Utilizing Human Embryonic Stem Cells $609,999
University of California, Santa Cruz David Feldheim SEED Grant Assessing the role of Eph/ephrin signaling in hESC growth and differentiation $499,999
University of California, Los Angeles William Lowry SEED Grant Modeling Human Embryonic Development with Human Embryonic Stem Cells $571,575
Sanford-Burnham Medical Research Institute Ziwei Huang SEED Grant New Chemokine-Derived Therapeutics Targeting Stem Cell Migration $759,000
University of California, Los Angeles Siavash Kurdistani SEED Grant Cellular epigenetic diversity as a blueprint for defining the identity and functional potential of human embryonic stem cells $641,047
Stanford University Krishna Shenoy SEED Grant Technology for hESC-Derived Cardiomyocyte Differentiation and Optimization of Graft-Host Integration in Adult Myocardium $634,287
University of California, San Diego Catriona Jamieson SEED Grant Derivation and Characterization of Cancer Stem Cells from Human ES Cells $642,500
Stanford University Calvin Kuo SEED Grant Differentiation of Human Embryonic Stem Cells to Intestinal Fates $578,943
Stanford University Mark Kay SEED Grant Novel vectors for gene transfer into human ES cells $640,642
The J. David Gladstone Institutes Warner Greene SEED Grant The APOBEC3 Gene Family as Guardians of Genome Stability in Human Embryonic Stem Cells $777,467
University of California, Los Angeles Zoran Galic SEED Grant Genetic Enhancement of the Immune Response to Melanoma via hESC-derived T cells $642,501
University of California, San Diego Anirvan Ghosh SEED Grant Generation of forebrain neurons from human embryonic stem cells $612,075
University of California, Santa Cruz Bin Chen SEED Grant In vitro differentiation of hESCs into corticospinal motor neurons $500,000
Sanford-Burnham Medical Research Institute Huei-sheng Chen SEED Grant Development of Neuro-Coupled Human Embryonic Stem Cell-Derived Cardiac Pacemaker Cells. $744,639
Stanford University John Cooke SEED Grant EC regeneration in cerebrovascular ischemia: role of NO $658,125
University of California, San Diego Shu Chien SEED Grant Combinatorial Platform for Optimizing Microenvironments to Control hESC Fate $638,140
The Salk Institute for Biological Studies Senyon Choe SEED Grant A method to maintain and propagate pluripotent human ES cells $796,348
Sanford-Burnham Medical Research Institute Gregg Duester SEED Grant Retinoic Acid-FGF Antagonism during Motor Neuron Differentiation of Human ES Cells $759,000
University of California, Los Angeles Irvin Chen SEED Grant Genetic modification of the human genome to resist HIV-1 infection and/or disease progression $642,652
University of California, San Francisco Robert Blelloch SEED Grant MicroRNA Regulation of Human Embryonic Stem Cell Self-Renewal and Differentiation $631,831
Buck Institute for Age Research Dale Bredesen SEED Grant Programmed Cell Death Pathways Activated in Embryonic Stem Cells $734,202
Human BioMolecular Research Institute John Cashman SEED Grant Discovering Potent Molecules with Human ESCs to Treat Heart Disease $714,654
University of California, San Diego Karl Willert Basic Biology I WNT signaling and the control of cell fate decisions in human pluripotent stem cells. $1,376,802
University of California, Los Angeles Robb Maclellan Basic Biology I Human Cardiovascular Progenitors, their Niches and Control of Self-renewal and Cell Fate $1,378,076
University of California, Davis Min Zhao Basic Biology I Directing migration of human stem cells with electric fields $1,052,715
University of Southern California Wange Lu Basic Biology I Defining the molecular mechanisms of somatic cell reprogramming $1,468,360
University of California, Los Angeles Luisa Iruela-Arispe Basic Biology I Molecular Characterization and Functional Exploration of Hemogenic Endothelium $1,371,477
University of California, Los Angeles Bennett Novitch Basic Biology I Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons $1,363,262
University of Southern California Martin Pera Basic Biology I The stem cell microenvironment in the maintenance of pluripotency and reprogramming $1,440,822
University of California, Los Angeles Michael Teitell Basic Biology I Mitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer $1,323,029
Stanford University Susan McConnell Basic Biology I Identification and characterization of human ES-derived DA neuronal subtypes $1,407,076
University of California, San Diego Eugene Yeo Basic Biology I RNA Binding Protein-mediated Post-transcriptional Networks Regulating HPSC Pluripotency $1,376,802
Stanford University Julien Sage Basic Biology I The retinoblastoma (RB) gene family in cellular reprogramming $1,436,185
Stanford University Helen Blau Basic Biology I Molecular Mechanisms of Reprogramming towards Pluripotency $1,414,841
Western University of Health Sciences Douglas Ethell New Faculty I ES-Derived Cells for the Treatment of Alzheimer's Disease $2,120,833
The J. David Gladstone Institutes Sheng Ding New Faculty I Reprogramming of human somatic cells back to pluripotent embryonic stem cells $2,943,375
University of California, Santa Cruz Camilla Forsberg New Faculty I Mechanisms of Stem Cell Fate Decisions $2,330,111
University of California, Berkeley Irina Conboy New Faculty I Identification of hESC-mediated molecular mechanism that positively regulates the regenerative capacity of post-natal tissues $2,246,020
University of California, Irvine Frank LaFerla Early Translational I Neural Stem Cells as a Developmental Candidate to Treat Alzheimer Disease $3,599,997
University of California, San Diego Yang Xu Early Translational I Developing induced pluripotent stem cells into human therapeutics and disease models $5,165,028
Scripps Research Institute Jeanne Loring Early Translational I Ensuring the safety of cell therapy: a quality control pipeline for cell purification and validation $6,292,290
Stanford University Anne Brunet New Faculty I Molecular mechanisms involved in adult neural stem cell maintenance $2,348,520
Stanford University Michael Longaker Early Translational I Enhancing healing via Wnt-protein mediated activation of endogenous stem cells $5,767,050
University of California, Los Angeles Gabriel Travis Early Translational I Development of a Stem Cell-based Transplantation Strategy for Treating Age-related Macular Degeneration $5,503,069
University of California, Irvine Michael Drake Major Facilities No Title $27,156,000
Sanford-Burnham Medical Research Institute Mark Mercola Disease Team Planning "Stem Cell Therapies for Heart Failure" $53,150
University of California, Los Angeles Gene Block Major Facilities No Title $19,854,900
Beckman Research Institute of City of Hope Michael Barish Disease Team Planning Genetically-modified neural stem cells for treatment of high-grade glioma $55,000
University of California, Merced John White Major Facilities No Title $4,359,480
University of California, San Diego Dennis Carson Disease Team Planning CIRM Planning Grant in Leukemia $55,000
University of California, Santa Barbara Glenn Lucas Major Facilities No Title $3,205,800
Stanford University Robert Robbins Disease Team Planning {REDACTED} Cardiovascular Regenerative Team $55,000
University of California, Santa Cruz Margaret Delaney Major Facilities No Title $7,191,950
University of California, Los Angeles Stanley Carmichael Disease Team Planning Development of a Stem Cell Therapy to Promote Functional Recovery in Stroke $44,792
University of California, San Francisco Jeffrey Bluestone Disease Team Planning A CIRM Disease Team for the Treatment and Cure of Diabetes $55,000
University of California, San Francisco A. Washington Major Facilities No Title $34,862,400
University of Southern California David Woodley Disease Team Planning Clinical Regenerative Wound Healing With Stem Cells $42,574
University of Southern California Chrysostomos Nikias Major Facilities No Title $26,972,500
University of California, San Francisco Jeffrey Lotz Disease Team Planning A CIRM Disease Team for the Repair of Traumatically Injured and Arthritic Cartilage $55,000
University of Southern California Mark Humayun Disease Team Planning Stem cell based treatment strategy for Age-related Macular Degeneration (AMD) $50,001
The Salk Institute for Biological Studies Samuel Pfaff Disease Team Planning Motor neuron diseases: Finding cures through basic, translational, and clinical collaboration $54,798
The J. David Gladstone Institutes Deepak Srivastava Disease Team Planning Pluripotent Stem Cell–Based Therapy for Heart Disease $53,972
ViaCyte, Inc. Emmanuel Baetge Disease Team Planning Development of a Cell Replacement Therapy Product for Insulin Dependent Diabetes $48,950
Stanford University Thomas Rando Disease Team Planning Stem Cell Therapy for Muscular Dystrophy $52,650
University of California, San Diego Lawrence Goldstein Disease Team Planning Human Stem Cell Approaches to Alzheimers Disease Therapies $55,000
ViaCyte, Inc. Howard Foyt Strategic Partnership I Preclinical and clinical testing of a stem cell-based combination product for insulin-dependent diabetes $10,075,070
University of California, Los Angeles Irvin Chen Disease Team Planning Stem Cell Therapy for AIDS- Disease Team Planning $52,500
Bluebird Bio David Davidson Strategic Partnership I A Phase 1/2, Open Label Study Evaluating the Safety and Efficacy of Gene Therapy in Subjects with β-Thalassemia by Transplantation of Autologous Hematopoietic Stem Cells [REDACTED] $9,363,335
Buck Institute for Age Research Xianmin Zeng Disease Team Planning Develop a cell replacement therapy for Parkinson's disease using human embryonic stem cells $55,000
University of California, Irvine Henry Klassen Disease Team Planning Stem cells for neuroprotection of photoreceptors in retinitis pigmentosa $37,367
Buck Institute for Age Research Mary McEachron Major Facilities No Title $20,500,000
Ludwig Institute for Cancer Research Webster Cavenee Disease Team Planning Stem Cell-Mediated Oncocidal Therapy of Primary & Metastatic Brain Tumors $55,000
Sanford Consortium for Regenerative Medicine Edward Holmes Major Facilities No Title $43,000,000
Children's Hospital of Oakland Research Institute Mark Walters Disease Team Planning CIRM Disease Team Planning Award $55,000
Stanford University John Hennessy Major Facilities No Title $43,578,000
Cedars-Sinai Medical Center Eduardo Marbán Disease Team Planning {REDACTED} Heart Disease Regenerative Medicine Team Planning Award $46,886
University of California, Berkeley George Breslauer Major Facilities No Title $20,183,500
The Parkinson's Institute Dennis Steindler Research Leadership 10 Stem Cell Pathologies in Parkinson’s disease as a key to Regenerative Strategies $6,718,471
University of California, Irvine Leslie Thompson Disease Team Planning Huntington's Disease Team $54,618
University of California, Davis Larry Vanderhoef Major Facilities No Title $20,082,400
University of Southern California Andrew McMahon Research Leadership 10 Repair and regeneration of the nephron $5,672,206
Children's Hospital of Los Angeles Donald Kohn Disease Team Planning STEM CELL GENE THERAPY FOR SICKLE CELL DISEASE $33,110
University of California, San Francisco Holger Willenbring Early Translational III Generation of safe and therapeutically effective human induced hepatocyte-like cells $1,544,170
Cedars-Sinai Medical Center Robert Baloh New Faculty Physician Scientist Human iPSC modeling and therapeutics for degenerative peripheral nerve disease $3,031,737
University of California, Davis Nancy Lane Disease Team Therapy Planning I Increasing the endogenous mesenchymal stem cells to the bone surface to treat osteoporosis $110,000
The J. David Gladstone Institutes Deepak Srivastava Basic Biology III Mechanisms of Direct Cardiac Reprogramming $1,708,560
The J. David Gladstone Institutes Deepak Srivastava Early Translational III Direct Cardiac Reprogramming for Heart Regeneration $6,319,110
Beckman Research Institute of City of Hope Jiing-Kuan Yee Basic Biology III Use of human iPS cells to study spinal muscular atrophy $1,268,868
Cedars-Sinai Medical Center Dan Gazit Disease Team Therapy Planning I Genetically Engineered Mesenchymal Stem Cells for the Treatment of Vertebral Compression Fractures. $109,743
Stanford University Helen Blau Early Translational III Local Delivery of Rejuvenated Old Muscle Stem Cells to Increase Strength in Aged Patients $1,825,920
University of California, Berkeley Song Li Basic Biology III Induced Pluripotent Stem Cells for Tissue Regeneration $1,341,064
Geron Corporation Jane Lebkowski Targeted Clinical Development Evaluation of Safety and Preliminary Efficacy of Escalating Doses of GRNOPC1 in Subacute Spinal Cord Injury $24,846,856
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Planning I Stem Cells Secreting GDNF for the Treatment of ALS $89,834
Stanford University Sean Wu Basic Biology III Elucidating Molecular Basis of Hypertrophic Cardiomyopathy with Human Induced Pluripotent Stem Cells $1,425,600
Total:
$420,269,933.00

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