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Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
University of California, Irvine Frank LaFerla SEED Grant Development of human ES cell lines as a model system for Alzheimer disease drug discovery $492,750
University of California, San Francisco Linda Giudice SEED Grant Human Embryonic Stem Cell Differentiation to Trophoblast: Basic Biology and Clinical Translation to Improve Human Fertility $640,399
University of California, San Francisco Su Guo SEED Grant Identifying small molecules that stimulate the differentiation of hESCs into dopamine-producing neurons $564,309
University of Southern California David Hinton SEED Grant Therapeutic potential of Retinal Pigment Epithelial cell lines derived from hES cells for retinal degeneration. $684,322
University of California, Irvine Michelle Khine SEED Grant Micro Platform for Controlled Cardiac Myocyte Differentiation $363,707
University of Southern California Wange Lu SEED Grant Regulation of human neural progenitor cell proliferation by Ryk-mediated Wnt signaling $668,987
Children's Hospital of Los Angeles Elizabeth Lawlor SEED Grant hESC as tools to investigate the neural crest origin of Ewing's sarcoma $675,001
University of California, San Diego Sylvia Evans SEED Grant Specification of Ventricular Myocyte and Pacemaker Lineages Utilizing Human Embryonic Stem Cells $609,999
University of California, Santa Cruz David Feldheim SEED Grant Assessing the role of Eph/ephrin signaling in hESC growth and differentiation $499,999
University of California, Los Angeles William Lowry SEED Grant Modeling Human Embryonic Development with Human Embryonic Stem Cells $571,575
Sanford-Burnham Medical Research Institute Ziwei Huang SEED Grant New Chemokine-Derived Therapeutics Targeting Stem Cell Migration $759,000
University of California, Los Angeles Siavash Kurdistani SEED Grant Cellular epigenetic diversity as a blueprint for defining the identity and functional potential of human embryonic stem cells $641,047
Stanford University Krishna Shenoy SEED Grant Technology for hESC-Derived Cardiomyocyte Differentiation and Optimization of Graft-Host Integration in Adult Myocardium $634,287
University of California, San Diego Catriona Jamieson SEED Grant Derivation and Characterization of Cancer Stem Cells from Human ES Cells $642,500
Stanford University Calvin Kuo SEED Grant Differentiation of Human Embryonic Stem Cells to Intestinal Fates $578,943
Stanford University Mark Kay SEED Grant Novel vectors for gene transfer into human ES cells $640,642
The J. David Gladstone Institutes Warner Greene SEED Grant The APOBEC3 Gene Family as Guardians of Genome Stability in Human Embryonic Stem Cells $777,467
University of California, Los Angeles Zoran Galic SEED Grant Genetic Enhancement of the Immune Response to Melanoma via hESC-derived T cells $642,501
University of California, San Diego Anirvan Ghosh SEED Grant Generation of forebrain neurons from human embryonic stem cells $612,075
Palo Alto Institute for Research and Education, Inc. Tony Wyss-Coray Basic Biology II Systemic Protein Factors as Modulators of the Aging Neurogenic Niche $1,522,800
University of California, Santa Cruz Bin Chen SEED Grant In vitro differentiation of hESCs into corticospinal motor neurons $500,000
Sanford-Burnham Medical Research Institute Huei-sheng Chen SEED Grant Development of Neuro-Coupled Human Embryonic Stem Cell-Derived Cardiac Pacemaker Cells. $744,639
Stanford University John Cooke SEED Grant EC regeneration in cerebrovascular ischemia: role of NO $658,125
University of California, San Diego Shu Chien SEED Grant Combinatorial Platform for Optimizing Microenvironments to Control hESC Fate $638,140
The Salk Institute for Biological Studies Senyon Choe SEED Grant A method to maintain and propagate pluripotent human ES cells $796,348
University of California, Irvine Marian Waterman Basic Biology II TCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal $1,277,101
Sanford-Burnham Medical Research Institute Gregg Duester SEED Grant Retinoic Acid-FGF Antagonism during Motor Neuron Differentiation of Human ES Cells $759,000
University of California, San Diego Dong-Er Zhang Basic Biology II RUNX1 in maintenance, expansion, and differentiation of therapeutic pluripotent stem cells $1,371,540
iPierian, Inc. John Dimos Basic Biology II Cellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency $1,458,000
University of California, Los Angeles Irvin Chen SEED Grant Genetic modification of the human genome to resist HIV-1 infection and/or disease progression $642,652
University of California, San Francisco Robert Blelloch SEED Grant MicroRNA Regulation of Human Embryonic Stem Cell Self-Renewal and Differentiation $631,831
Buck Institute for Age Research Dale Bredesen SEED Grant Programmed Cell Death Pathways Activated in Embryonic Stem Cells $734,202
Human BioMolecular Research Institute John Cashman SEED Grant Discovering Potent Molecules with Human ESCs to Treat Heart Disease $714,654
University of California, Los Angeles Douglas Black Basic Biology II Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,350,994
University of California, Los Angeles Yong Kim Basic Biology II Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells $1,259,371
Stanford University Steven Artandi Basic Biology II Self-renewal and senescence in iPS cells derived from patients with a stem cell disease $1,430,908
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology II Endothelial cells and ion channel maturation of human stem cell-derived cardiomyocytes $1,823,362
University of California, San Francisco John Rubenstein Basic Biology II MGE Enhancers to Select for Interneuron Precursors Produced from Human ES Cells $1,387,800
Stanford University Garry Nolan Basic Biology II Kinase signaling analysis of iPS cell reprogramming and differentiation $1,447,956
University of California, Irvine Aileen Anderson Basic Biology II Role of the microenvironment in human iPS and NSC fate and tumorigenesis $1,284,921
University of California, San Diego Karl Willert Basic Biology I WNT signaling and the control of cell fate decisions in human pluripotent stem cells. $1,376,802
University of California, San Diego Kun-Liang Guan Basic Biology II The function of YAP in human embryonic stem cells $1,340,565
University of California, Los Angeles Robb Maclellan Basic Biology I Human Cardiovascular Progenitors, their Niches and Control of Self-renewal and Cell Fate $1,378,076
University of California, Los Angeles Benhur Lee Basic Biology II The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation $1,371,936
University of California, Davis Min Zhao Basic Biology I Directing migration of human stem cells with electric fields $1,052,715
Stanford University Aaron Hsueh Basic Biology II Maturation of Human Oocytes for SCNT and Embryonic Stem Cell Derivation $1,432,197
University of Southern California Wange Lu Basic Biology I Defining the molecular mechanisms of somatic cell reprogramming $1,468,360
The Salk Institute for Biological Studies Ronald Evans Basic Biology II Molecular Characterization and Functional Exploration of Nuclear Receptors in hiPSCs $1,712,880
University of California, Los Angeles Luisa Iruela-Arispe Basic Biology I Molecular Characterization and Functional Exploration of Hemogenic Endothelium $1,371,477
University of California, Los Angeles Bennett Novitch Basic Biology I Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons $1,363,262
University of California, Davis Eric Kurzrock Basic Biology II Differentiation of Human Embryonic Stem Cells into Urothelium $1,328,400
University of Southern California Martin Pera Basic Biology I The stem cell microenvironment in the maintenance of pluripotency and reprogramming $1,440,822
University of California, Los Angeles Michael Teitell Basic Biology I Mitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer $1,323,029
Stanford University Susan McConnell Basic Biology I Identification and characterization of human ES-derived DA neuronal subtypes $1,407,076
University of California, San Diego Eugene Yeo Basic Biology I RNA Binding Protein-mediated Post-transcriptional Networks Regulating HPSC Pluripotency $1,376,802
Stanford University Julien Sage Basic Biology I The retinoblastoma (RB) gene family in cellular reprogramming $1,436,185
Stanford University Helen Blau Basic Biology I Molecular Mechanisms of Reprogramming towards Pluripotency $1,414,841
Western University of Health Sciences Douglas Ethell New Faculty I ES-Derived Cells for the Treatment of Alzheimer's Disease $2,120,833
The J. David Gladstone Institutes Sheng Ding New Faculty I Reprogramming of human somatic cells back to pluripotent embryonic stem cells $2,943,375
University of California, Santa Cruz Camilla Forsberg New Faculty I Mechanisms of Stem Cell Fate Decisions $2,330,111
University of California, San Diego Lawrence Goldstein Traning Grant I-1 Interdisciplinary Stem Cell Training Program at UCSD $3,684,349
University of California, Los Angeles Gay Crooks Transplantation Immunology Engineering Thymic Regeneration to Induce Tolerance $1,357,398
Stanford University Irving Weissman Tools and Technologies II Antibody tools to deplete or isolate teratogenic, cardiac, and blood stem cells from hESCs $1,869,487
University of California, San Diego Yang Xu Transplantation Immunology Induction of immune tolerance to human embryonic stem cell-derived allografts $1,193,292
University of California, Los Angeles Richard Gatti Tools and Technologies II Use of hiPSCs to develop lead compounds for the treatment of genetic diseases $1,833,054
University of California, Berkeley Irina Conboy New Faculty I Identification of hESC-mediated molecular mechanism that positively regulates the regenerative capacity of post-natal tissues $2,246,020
University of California, San Diego Karl Willert Tools and Technologies II Homologous recombination in human pluripotent stem cells using adeno-associated virus. $1,993,586
University of California, Irvine Frank LaFerla Early Translational I Neural Stem Cells as a Developmental Candidate to Treat Alzheimer Disease $3,599,997
University of California, San Diego Yang Xu Early Translational I Developing induced pluripotent stem cells into human therapeutics and disease models $5,165,028
Scripps Research Institute Jeanne Loring Early Translational I Ensuring the safety of cell therapy: a quality control pipeline for cell purification and validation $6,292,290
Sanford-Burnham Medical Research Institute Mark Mercola Traning Grant I-2 Burnham Institute CIRM Stem Cell Training Grant (Type II) $1,489,640
Scripps Research Institute Jeanne Loring Transplantation Immunology Thymus based tolerance to stem cell therapies $1,269,844
Stanford University Anne Brunet New Faculty I Molecular mechanisms involved in adult neural stem cell maintenance $2,348,520
University of California, San Francisco Daniel Lim Tools and Technologies II Development and preclinical testing of new devices for cell transplantation to the brain. $1,831,723
University of California, San Francisco Tippi MacKenzie Transplantation Immunology Maternal and Fetal Immune Responses to In Utero Hematopoietic Stem Cell Transplantation $1,324,229
University of California, Berkeley David Raulet Transplantation Immunology Inactivating NK cell reactivity to facilitate transplantation of stem cell derived tissue $958,808
Stanford University Michael Longaker Early Translational I Enhancing healing via Wnt-protein mediated activation of endogenous stem cells $5,767,050
Stanford University Kenneth Weinberg Transplantation Immunology “Engineered immune tolerance by Stem Cell-derived thymic regeneration” $1,415,836
University of California, Los Angeles Gabriel Travis Early Translational I Development of a Stem Cell-based Transplantation Strategy for Treating Age-related Macular Degeneration $5,503,069
University of California, San Diego Lawrence Goldstein Tools and Technologies II Developing a method for rapid identification of high-quality disease specific hIPSC lines $1,816,157
University of California, Santa Barbara Glenn Lucas Major Facilities No Title $3,205,800
The Parkinson's Institute Dennis Steindler Research Leadership 10 Stem Cell Pathologies in Parkinson’s disease as a key to Regenerative Strategies $6,718,471
Stanford University Robert Robbins Disease Team Planning {REDACTED} Cardiovascular Regenerative Team $55,000
University of California, Santa Cruz Margaret Delaney Major Facilities No Title $7,191,950
University of Southern California Andrew McMahon Research Leadership 10 Repair and regeneration of the nephron $5,672,206
University of California, Los Angeles Stanley Carmichael Disease Team Planning Development of a Stem Cell Therapy to Promote Functional Recovery in Stroke $44,792
University of California, San Francisco Jeffrey Bluestone Disease Team Planning A CIRM Disease Team for the Treatment and Cure of Diabetes $55,000
University of California, San Francisco A. Washington Major Facilities No Title $34,862,400
University of Southern California David Woodley Disease Team Planning Clinical Regenerative Wound Healing With Stem Cells $42,574
University of Southern California Chrysostomos Nikias Major Facilities No Title $26,972,500
University of California, San Francisco Jeffrey Lotz Disease Team Planning A CIRM Disease Team for the Repair of Traumatically Injured and Arthritic Cartilage $55,000
University of Southern California Mark Humayun Disease Team Planning Stem cell based treatment strategy for Age-related Macular Degeneration (AMD) $50,001
The Salk Institute for Biological Studies Samuel Pfaff Disease Team Planning Motor neuron diseases: Finding cures through basic, translational, and clinical collaboration $54,798
The J. David Gladstone Institutes Deepak Srivastava Disease Team Planning Pluripotent Stem Cell–Based Therapy for Heart Disease $53,972
ViaCyte, Inc. Emmanuel Baetge Disease Team Planning Development of a Cell Replacement Therapy Product for Insulin Dependent Diabetes $48,950
Stanford University Thomas Rando Disease Team Planning Stem Cell Therapy for Muscular Dystrophy $52,650
University of California, San Diego Lawrence Goldstein Disease Team Planning Human Stem Cell Approaches to Alzheimers Disease Therapies $55,000
University of California, Los Angeles Irvin Chen Disease Team Planning Stem Cell Therapy for AIDS- Disease Team Planning $52,500
Buck Institute for Age Research Xianmin Zeng Disease Team Planning Develop a cell replacement therapy for Parkinson's disease using human embryonic stem cells $55,000
University of California, Irvine Henry Klassen Disease Team Planning Stem cells for neuroprotection of photoreceptors in retinitis pigmentosa $37,367
Total:
$203,418,906.00

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