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Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
The J. David Gladstone Institutes Deepak Srivastava Shared Labs CIRM Shared Human Embryonic Stem Cell Core Laboratory $2,621,345
University of California, Santa Cruz Lindsay Hinck Shared Labs Shared Stem Cell Facility $3,588,740
University of California, Los Angeles Owen Witte Shared Labs CIRM Shared Research Laboratories $3,740,497
The Salk Institute for Biological Studies Inder Verma Shared Labs Shared viral vector facility for genetic manipulation of human ES cell $4,316,515
University of California, Irvine Peter Donovan Shared Labs Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $5,572,979
Children's Hospital of Los Angeles David Warburton Shared Labs hESC Facility $3,756,666
University of Southern California Andrew McMahon Shared Labs Center for Stem Cell and Regenerative Medicine: Shared Research Laboratory and Course in Current Protocols in Human Embryonic Stem Cell Research $5,355,969
University of California, San Francisco Linda Giudice Shared Labs Shared Research and Teaching Laboratory: a Non-Federal Human Embryonic Stem Cell Resource for the Bay Area Community $5,546,877
University of California, Santa Barbara Dennis Clegg Shared Labs Laboratory for Stem Cell Biology and Engineering $3,161,329
University of California, Davis Alice Tarantal Shared Labs Translational Human Embryonic Stem Cell Shared Research Facility $3,709,631
University of California, Berkeley David Schaffer Shared Labs Human Embryonic Stem Cell Shared Research Laboratory $2,929,237
University of California, Riverside Prudence Talbot Shared Labs A Stem Cell Core Facility for Studying Human Embryonic Stem Cell Differentiation $3,658,353
Sanford-Burnham Medical Research Institute Evan Snyder Shared Labs Collaborative Laboratory for Human Embryonic Stem Cell Research $4,762,725
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,382,400
Stanford University Howard Chang Basic Biology IV Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
The J. David Gladstone Institutes Steven Finkbeiner Basic Biology IV Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,506,420
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
The J. David Gladstone Institutes Benoit Bruneau Basic Biology IV Epigenetic regulation of human cardiac differentiation $1,708,560
Cedars-Sinai Medical Center Eduardo Marbán Basic Biology IV Mechanism of heart regeneration by cardiosphere-derived cells $1,367,604
University of California, San Diego Miles Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
Stanford University Ben Barres Basic Biology IV Phenotyping Human Astrocytes in Health and Disease $1,385,517
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
Stanford University Roel Nusse Basic Biology IV Asymmetric stem cell division oriented by a local self-renewing signal $1,195,811
University of California, San Diego Eugene Yeo Basic Biology IV Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,393,200
University of California, San Francisco Barbara Panning Basic Biology IV Investigation of the role of O-GlcNAcylation in SOX2 function during reprogramming $1,285,214
University of California, Berkeley Robert Tjian Basic Biology IV Transcriptional regulation of pluripotency in human embryonic stem cells $1,220,968
Stanford University Anne Brunet Basic Biology IV Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
Stanford University Michael Cleary Basic Biology IV Prostaglandin pathway regulation of self-renwal in hematopoietic and leukemia stem cells $1,244,455
University of California, Davis Deborah Lieu Basic Biology IV Induction of Pluripotent Stem Cell-Derived Pacemaking Cells $1,334,880
University of California, San Francisco Miguel Ramalho-Santos Basic Biology IV Genetic dissection of human cellular reprogramming to pluripotency $1,184,883
Buck Institute for Age Research Deepak Lamba Basic Biology IV 3D Modeling of Retina using Polymer Scaffolds for Understanding Disease Pathogenesis $1,526,319
University of California, San Francisco Jeremy Reiter Basic Biology IV Modeling disease in human embryonic stem cells using new genetic tools $1,387,800
Stanford University Alexander Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,064,224
University of California, San Diego George Sen Basic Biology IV Regulation of Epidermal Self-Renewal and Differentiation by Histone and DNA Demethylases. $1,080,000
Beckman Research Institute of City of Hope Yanhong Shi Basic Biology IV Modeling Alexander disease using patient-specific induced pluripotent stem cells $1,367,172
University of California, Los Angeles Kathrin Plath Basic Biology IV Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
University of California, San Diego Maike Sander Basic Biology IV Deciphering transcriptional control of pancreatic beta-cell maturation in vitro $1,391,400
The J. David Gladstone Institutes Sheng Ding Basic Biology IV A new paradigm of lineage-specific reprogramming $1,708,560
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology IV Studying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells $1,582,606
Stanford University Michele Calos New Cell Lines Safe, efficient creation of human induced pluripotent stem cells without the use of retroviruses $1,406,875
University of California, San Francisco Miguel Ramalho-Santos SEED Grant Transcriptional Regulation of Human Embryonic Stem Cells $618,901
University of California, Los Angeles Amander Clark New Cell Lines Generation of Pluripotent Cell Lines from Human Embryos $1,177,648
University of Southern California Qilong Ying SEED Grant Self-renewal of human embryonic stem cells $663,209
The J. David Gladstone Institutes Bruce Conklin New Cell Lines Induced Pluripotent Stem Cells for Cardiovascular Diagnostics $1,708,560
University of California, San Francisco Thea Tlsty SEED Grant Role of the tumor suppressor gene, p16INK4a, in regulating stem cell phenotypes in embryonic stem cells and human epithelial cells. $639,150
University of California, San Diego Steve Dowdy New Cell Lines Protein transduction of transcription factors: a non-genetic approach to generate new pluripotent cell lines from human skin. $1,387,800
University of California, Irvine Charles Limoli SEED Grant Using human embryonic stem cells to treat radiation-induced stem cell loss: Benefits vs cancer risk $625,617
University of California, San Francisco Valerie Weaver SEED Grant Force, Dimensionality and Stem Cell Fate $561,082
University of California, San Francisco Susan Fisher New Cell Lines Optimization of Human Embryonic Stem Cell Derivation Techniques and Production/Distribution of GMP-Grade Lines $1,383,419
Sanford-Burnham Medical Research Institute Alexey Terskikh SEED Grant Analysis of Candidate Neural Crest Cells Derived from Human ES Cells $759,000
The J. David Gladstone Institutes Robert Farese New Cell Lines Establishment of Frontotemporal Dementia Patient-Specific Induced Pluripotent Stem (iPS) Cell Lines with Defined Genetic Mutations $1,708,560
The Salk Institute for Biological Studies Fred Gage New Cell Lines Development of Induced Pluripotent Stem Cells for Modeling Human Disease $1,737,720
Stanford University Aaron Hsueh SEED Grant Patient-specific cells with nuclear transfer $656,074
University of California, San Francisco Long-cheng Li New Cell Lines Induction of pluripotent stem cells by small RNA-guided transcriptional activation $1,375,144
University of Southern California Peter Laird SEED Grant Screening for Oncogenic Epigenetic Alterations in Human ES Cells $685,000
Stanford University Michael Longaker New Cell Lines Derivation and analysis of pluripotent stem cell lines with inherited TGF-b mediated disorders from donated IVF embryos and reprogrammed adult skin fibroblasts $1,424,412
University of California, Irvine Thomas Lane SEED Grant Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination $425,594
University of California, San Francisco Miguel Ramalho-Santos New Cell Lines Somatic cell age and memory in the generation of iPS cells $1,307,201
Sanford-Burnham Medical Research Institute Zhuohua Zhang SEED Grant Modeling Parkinson's Disease Using Human Embryonic Stem Cells $758,999
University of California, Riverside Frank Sauer SEED Grant Non-coding RNA as tool for the active control of stem cell differentiation $595,469
Stanford University Renee Reijo Pera New Cell Lines Derivation and comparative analysis of human pluripotent ESCs, iPSCs and SSCs: Convergence to an embryonic phenotype $1,410,042
University of Southern California Martin Pera New Cell Lines New Technology ForThe Derivation of Human Pluripotent Stem Cell Lines For Clinical Use $1,387,508
University of California, San Francisco Holger Willenbring SEED Grant Induction of pluripotency in fibroblasts by fusion with enucleated human embryonic stem cell syncytia $342,962
The J. David Gladstone Institutes Sheng Ding New Cell Lines Derivation of New ICM-stage hESCs $1,719,468
University of California, Davis Ebenezer Yamoah SEED Grant Hair Cells and Spiral Ganglion Neuron Differentiation from Human Embryonic Stem Cells $469,327
University of California, San Diego Binhai Zheng SEED Grant Genetic manipulation of human embryonic stem cells and its application in studying CNS development and repair $642,361
University of California, Irvine Kyoko Yokomori SEED Grant Derivation and characterization of human ES cells from FSHD embryos $632,500
University of California, Berkeley Carolyn Bertozzi SEED Grant Profiling surface glycans and glycoprotein expression of human embryonic stem cells $498,409
Stanford University Kenneth Weinberg SEED Grant Embryonic stem cell-derived thymic epithelial cells $658,057
Stanford University Joseph Wu SEED Grant In Vivo Imaging of Human Embryonic Stem Cell Derivatives and Tumorigenicity $658,123
The J. David Gladstone Institutes Fen-Biao Gao SEED Grant MicroRNAs in Human Stem Cell Differentiation and Mental Disorders $791,000
Stanford University Joanna Wysocka SEED Grant Role of Chromatin Modifiers in Regulating Human Embryonic Stem Cell Pluripotency $658,126
University of California, Los Angeles Noriyuki Kasahara SEED Grant Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $469,219
University of California, Irvine Leslie Thompson New Cell Lines New Cell Lines for Huntington's Disease $1,369,800
University of California, San Francisco Heike Daldrup-Link SEED Grant Labeling of human embryonic stem cells with iron oxide nanoparticles and fluorescent dyes for a non-invasive cell depiction with MR imaging and optical imaging $251,088
Stanford University Phillip Yang SEED Grant In Vivo Molecular Magnetic Resonance Imaging of Human Embryonic Stem Cells in Murine Model of Myocardial Infarction $658,125
University of California, Los Angeles Zack Jerome New Cell Lines Generation of clinical grade human iPS cells $1,382,400
University of California, Irvine Vincent Procaccio SEED Grant Mitochondrial Dysfunction in Embryonic Stem Cells $632,500
Sanford-Burnham Medical Research Institute Zhuohua Zhang New Cell Lines Derivation of Parkinson's Disease Coded-Stem Cells (PD-SCs) $1,589,760
University of California, Los Angeles Hanna Mikkola SEED Grant Improving microenvironments to promote hematopoietic stem cell development from human embryonic stem cells $577,037
University of California, Davis A. Reddi SEED Grant hESCs for Articular Cartilage Regeneration $367,650
Stanford University Julie Baker New Cell Lines Derivation of hESC Lines with Disease Lesions $1,424,412
University of California, Irvine Brian Cummings SEED Grant The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $619,223
Beckman Research Institute of City of Hope Timothy O'Connor SEED Grant Sources of Genetic Instability in Human Embryonic Stem Cells. $357,978
University of California, Irvine Grant MacGregor SEED Grant Production of Oocytes from Human ES Cells $623,781
University of California, Riverside Michael Pirrung SEED Grant Stem Cell Survival and Differentiation Through Chemical Genetics $543,987
Ludwig Institute for Cancer Research Bing Ren SEED Grant Mapping the transcriptional regulatory elements in the genome of hESC $691,489
University of California, Berkeley Ellen Robey SEED Grant In Vitro Differentiation of T cells from Human Embryonic Stem Cells. $499,999
The J. David Gladstone Institutes Eric Verdin SEED Grant Role of HDAC in human stem cells pluripotentiality and differentiation $790,999
University of California, San Diego Cornelis Murre SEED Grant Generation of long-term cultures of human hematopoietic multipotent progenitors from embryonic stem cells $538,211
Sanford-Burnham Medical Research Institute Robert Oshima SEED Grant Trophoblast differentiation of human ES cells. $748,240
The Salk Institute for Biological Studies Samuel Pfaff SEED Grant Gene regulatory mechanisms that control spinal neuron differentiation from hES cells. $807,749
University of California, San Francisco Didier Stainier SEED Grant Endodermal differentiation of human ES cells $635,242
University of California, Los Angeles Michael Teitell SEED Grant Role of Mitochondria in Self-Renewal Versus Differentiation of Human Embryonic Stem Cells $635,024
Stanford University Julien Sage SEED Grant Functions of RB family proteins in human embryonic stem cells $520,777
Scripps Research Institute Peter Schultz SEED Grant A Chemical Approach to Stem Cell Biology $784,900
Sanford-Burnham Medical Research Institute Hudson Freeze SEED Grant Role of Glycans in Human Embryonic Stem Cell Conversion to Neural Precursor Cells $759,000
Stanford University Susan McConnell SEED Grant Optimization of guidance response in human embryonic stem cell derived midbrain dopaminergic neurons in development and disease $633,170
Total:
$141,148,826.00

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