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Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
University of California, San Diego Shyni Varghese New Faculty II A Novel Microenvironment-Mediated Functional Skeletal Muscle from Human Embryonic Stem Cells and their In Vivo Engraftment $2,300,569
University of California, San Francisco Robert Blelloch New Faculty II Mechanisms of small RNA regulation in early embryonic development $3,204,897
Children's Hospital of Los Angeles Tracy Grikscheit New Faculty II Mechanism of Tissue Engineered Small Intestine Formation $3,415,000
University of California, San Francisco Holger Willenbring New Faculty II Molecular dissection of adult liver regeneration to guide the generation of hepatocytes from pluripotent stem cells $3,207,510
The J. David Gladstone Institutes Yadong Huang New Faculty II Defining the Isoform-Specific Effects of Apolipoprotein E on the Development of iPS Cells into Functional Neurons in Vitro and in Vivo $2,847,600
University of California, San Diego Benjamin Yu New Faculty II Regulation of Adult Stem Cell Proliferation by RAS and Cell-Permeable Proteins $3,231,649
Stanford University Ching-Pin Chang New Faculty II VEGF signaling in adventitial stem cells in vascular physiology and disease $3,330,931
University of California, San Diego Catriona Jamieson New Faculty II Derivation and Characterization of Myeloproliferative Disorder Stem Cells from Human ES Cells $3,065,572
University of California, Irvine Edwin Monuki New Faculty II Mechanisms in Choroid Plexus Epithelial Development $3,169,328
University of Southern California Gage DeKoeyer Crump New Faculty II Skeletogenic Neural Crest Cells in Embryonic Development and Adult Regeneration of the Jaw $2,396,871
University of California, San Francisco Jeremy Reiter New Faculty II High throughput modeling of human neurodegenerative diseases in embryonic stem cells $2,259,092
University of California, Merced Kara McCloskey New Faculty II Building Cardiac Tissue from Stem Cells and Natural Matrices $1,706,255
University of California, Davis Paul Knoepfler New Faculty II Molecular mechanisms governing hESC and iPS cell self-renewal and pluripotency $2,158,161
University of California, San Francisco Samuel Pleasure Comprehensive Grant Human stem cell derived oligodendrocytes for treatment of stroke and MS $2,566,701
University of California, Irvine Vincent Procaccio SEED Grant Mitochondrial Dysfunction in Embryonic Stem Cells $632,500
Sanford-Burnham Medical Research Institute Zhuohua Zhang New Cell Lines Derivation of Parkinson's Disease Coded-Stem Cells (PD-SCs) $1,589,760
University of California, Los Angeles Zack Jerome Comprehensive Grant Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,516,831
University of California, Los Angeles Hanna Mikkola SEED Grant Improving microenvironments to promote hematopoietic stem cell development from human embryonic stem cells $577,037
University of California, Davis A. Reddi SEED Grant hESCs for Articular Cartilage Regeneration $367,650
Stanford University Julie Baker New Cell Lines Derivation of hESC Lines with Disease Lesions $1,424,412
University of California, Irvine Brian Cummings SEED Grant The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $619,223
Stanford University Christopher Zarins Comprehensive Grant Engineering a Cardiovascular Tissue Graft from Human Embryonic Stem Cells $2,618,704
Beckman Research Institute of City of Hope Timothy O'Connor SEED Grant Sources of Genetic Instability in Human Embryonic Stem Cells. $357,978
University of California, Irvine Grant MacGregor SEED Grant Production of Oocytes from Human ES Cells $623,781
Stanford University Michele Calos New Cell Lines Safe, efficient creation of human induced pluripotent stem cells without the use of retroviruses $1,406,875
University of California, Irvine Hans Keirstead Comprehensive Grant hESC-Derived Motor Neurons For the Treatment of Cervical Spinal Cord Injury $2,396,932
University of California, San Francisco Miguel Ramalho-Santos SEED Grant Transcriptional Regulation of Human Embryonic Stem Cells $618,901
University of Southern California Qilong Ying SEED Grant Self-renewal of human embryonic stem cells $663,209
University of California, Los Angeles Amander Clark New Cell Lines Generation of Pluripotent Cell Lines from Human Embryos $1,177,648
University of California, San Francisco Arnold Kriegstein Comprehensive Grant Derivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells $2,507,223
The J. David Gladstone Institutes Bruce Conklin New Cell Lines Induced Pluripotent Stem Cells for Cardiovascular Diagnostics $1,708,560
Stanford University Renee Reijo Pera Comprehensive Grant Human oocyte development for genetic, pharmacological and reprogramming applications $2,469,104
University of California, San Francisco Thea Tlsty SEED Grant Role of the tumor suppressor gene, p16INK4a, in regulating stem cell phenotypes in embryonic stem cells and human epithelial cells. $639,150
University of California, Irvine Charles Limoli SEED Grant Using human embryonic stem cells to treat radiation-induced stem cell loss: Benefits vs cancer risk $625,617
University of California, San Diego Steve Dowdy New Cell Lines Protein transduction of transcription factors: a non-genetic approach to generate new pluripotent cell lines from human skin. $1,387,800
The J. David Gladstone Institutes Deepak Srivastava Comprehensive Grant microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells $3,164,000
University of California, San Francisco Valerie Weaver SEED Grant Force, Dimensionality and Stem Cell Fate $561,082
Sanford-Burnham Medical Research Institute Stuart Lipton Comprehensive Grant MEF2C-Directed Neurogenesis From Human Embryonic Stem Cells $3,035,996
University of California, San Francisco Susan Fisher New Cell Lines Optimization of Human Embryonic Stem Cell Derivation Techniques and Production/Distribution of GMP-Grade Lines $1,383,419
University of California, Los Angeles Guoping Fan Comprehensive Grant Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair $2,516,613
Sanford-Burnham Medical Research Institute Alexey Terskikh SEED Grant Analysis of Candidate Neural Crest Cells Derived from Human ES Cells $759,000
Stanford University Irving Weissman Comprehensive Grant Prospective isolation of hESC-derived hematopoietic and cardiomyocyte stem cells $2,636,900
The J. David Gladstone Institutes Robert Farese New Cell Lines Establishment of Frontotemporal Dementia Patient-Specific Induced Pluripotent Stem (iPS) Cell Lines with Defined Genetic Mutations $1,708,560
University of California, San Francisco Susan Fisher Comprehensive Grant Constructing a fate map of the human embryo $2,532,388
University of California, Irvine Peter Donovan Comprehensive Grant Improved hES Cell Growth and Differentiation $2,509,438
The Salk Institute for Biological Studies Fred Gage New Cell Lines Development of Induced Pluripotent Stem Cells for Modeling Human Disease $1,737,720
The Salk Institute for Biological Studies Fred Gage Comprehensive Grant Molecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons $2,879,210
Stanford University Aaron Hsueh SEED Grant Patient-specific cells with nuclear transfer $656,074
University of California, San Francisco Andrew Leavitt Comprehensive Grant Understanding hESC-based Hematopoiesis for Therapeutic Benefit $2,566,702
University of California, San Francisco Long-cheng Li New Cell Lines Induction of pluripotent stem cells by small RNA-guided transcriptional activation $1,375,144
University of California, San Diego Lawrence Goldstein Comprehensive Grant Using Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer's Disease $2,512,664
University of Southern California Peter Laird SEED Grant Screening for Oncogenic Epigenetic Alterations in Human ES Cells $685,000
University of California, Irvine Douglas Wallace Comprehensive Grant The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $2,530,000
Stanford University Michael Longaker New Cell Lines Derivation and analysis of pluripotent stem cell lines with inherited TGF-b mediated disorders from donated IVF embryos and reprogrammed adult skin fibroblasts $1,424,412
University of California, San Diego Martin Marsala Comprehensive Grant Spinal ischemic paraplegia: modulation by human embryonic stem cell implant $2,445,716
University of California, Irvine Thomas Lane SEED Grant Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination $425,594
University of California, Los Angeles Gay Crooks Comprehensive Grant Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $2,551,088
Sanford-Burnham Medical Research Institute Zhuohua Zhang SEED Grant Modeling Parkinson's Disease Using Human Embryonic Stem Cells $758,999
University of California, San Francisco Miguel Ramalho-Santos New Cell Lines Somatic cell age and memory in the generation of iPS cells $1,307,201
Sanford-Burnham Medical Research Institute Mark Mercola Comprehensive Grant Chemical Genetic Approach to Production of hESC-derived Cardiomyocytes $3,036,002
University of California, Davis Mark Zern Comprehensive Grant An in vitro and in vivo comparison among three different human hepatic stem cell populations $2,504,614
University of California, Riverside Frank Sauer SEED Grant Non-coding RNA as tool for the active control of stem cell differentiation $595,469
Stanford University Renee Reijo Pera New Cell Lines Derivation and comparative analysis of human pluripotent ESCs, iPSCs and SSCs: Convergence to an embryonic phenotype $1,410,042
Stanford University Stefan Heller Comprehensive Grant Generation of inner ear sensory cells from human ES cells toward a cure for deafness $2,469,373
University of California, San Francisco Holger Willenbring SEED Grant Induction of pluripotency in fibroblasts by fusion with enucleated human embryonic stem cell syncytia $342,962
The J. David Gladstone Institutes Sheng Ding New Cell Lines Derivation of New ICM-stage hESCs $1,719,468
University of California, San Francisco Randall Lee Comprehensive Grant Embryonic Stem Cell-Derived Therapies Targeting Cardiac Ischemic Disease $2,524,617
University of Southern California Martin Pera New Cell Lines New Technology ForThe Derivation of Human Pluripotent Stem Cell Lines For Clinical Use $1,387,508
Stanford University Roel Nusse Comprehensive Grant Guiding the developmental program of human embryonic stem cells by isolated Wnt factors $2,354,820
University of California, Davis Ebenezer Yamoah SEED Grant Hair Cells and Spiral Ganglion Neuron Differentiation from Human Embryonic Stem Cells $469,327
University of California, San Diego Binhai Zheng SEED Grant Genetic manipulation of human embryonic stem cells and its application in studying CNS development and repair $642,361
University of California, Davis Alice Tarantal Comprehensive Grant Preclinical Model for Labeling, Transplant, and In Vivo Imaging of Differentiated Human Embryonic Stem Cells $2,257,040
University of California, Irvine Kyoko Yokomori SEED Grant Derivation and characterization of human ES cells from FSHD embryos $632,500
University of California, Berkeley Carolyn Bertozzi SEED Grant Profiling surface glycans and glycoprotein expression of human embryonic stem cells $498,409
Stanford University Kenneth Weinberg SEED Grant Embryonic stem cell-derived thymic epithelial cells $658,057
University of California, San Diego Yang Xu Comprehensive Grant Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells $2,570,000
Stanford University Joseph Wu SEED Grant In Vivo Imaging of Human Embryonic Stem Cell Derivatives and Tumorigenicity $658,123
Stanford University Julie Baker Comprehensive Grant Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cell $2,628,635
The J. David Gladstone Institutes Fen-Biao Gao SEED Grant MicroRNAs in Human Stem Cell Differentiation and Mental Disorders $791,000
Stanford University Joanna Wysocka SEED Grant Role of Chromatin Modifiers in Regulating Human Embryonic Stem Cell Pluripotency $658,126
University of California, San Francisco Harold Bernstein Comprehensive Grant Modeling Myocardial Therapy with Human Embryonic Stem Cells $2,229,140
University of California, Los Angeles Noriyuki Kasahara SEED Grant Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $469,219
University of California, Irvine Leslie Thompson New Cell Lines New Cell Lines for Huntington's Disease $1,369,800
Stanford University Theo Palmer Comprehensive Grant Immunology of neural stem cell fate and function $2,501,125
University of California, San Francisco Heike Daldrup-Link SEED Grant Labeling of human embryonic stem cells with iron oxide nanoparticles and fluorescent dyes for a non-invasive cell depiction with MR imaging and optical imaging $251,088
University of California, Los Angeles Zack Jerome New Cell Lines Generation of clinical grade human iPS cells $1,382,400
Stanford University Phillip Yang SEED Grant In Vivo Molecular Magnetic Resonance Imaging of Human Embryonic Stem Cells in Murine Model of Myocardial Infarction $658,125
University of California, Riverside Michael Pirrung SEED Grant Stem Cell Survival and Differentiation Through Chemical Genetics $543,987
Ludwig Institute for Cancer Research Bing Ren SEED Grant Mapping the transcriptional regulatory elements in the genome of hESC $691,489
University of California, Berkeley Ellen Robey SEED Grant In Vitro Differentiation of T cells from Human Embryonic Stem Cells. $499,999
The J. David Gladstone Institutes Eric Verdin SEED Grant Role of HDAC in human stem cells pluripotentiality and differentiation $790,999
University of California, San Diego Cornelis Murre SEED Grant Generation of long-term cultures of human hematopoietic multipotent progenitors from embryonic stem cells $538,211
Sanford-Burnham Medical Research Institute Robert Oshima SEED Grant Trophoblast differentiation of human ES cells. $748,240
The Salk Institute for Biological Studies Samuel Pfaff SEED Grant Gene regulatory mechanisms that control spinal neuron differentiation from hES cells. $807,749
University of California, San Francisco Didier Stainier SEED Grant Endodermal differentiation of human ES cells $635,242
University of California, Los Angeles Michael Teitell SEED Grant Role of Mitochondria in Self-Renewal Versus Differentiation of Human Embryonic Stem Cells $635,024
Stanford University Julien Sage SEED Grant Functions of RB family proteins in human embryonic stem cells $520,777
Scripps Research Institute Peter Schultz SEED Grant A Chemical Approach to Stem Cell Biology $784,900
University of California, Los Angeles Zoran Galic SEED Grant Genetic Enhancement of the Immune Response to Melanoma via hESC-derived T cells $642,501
University of California, San Diego Anirvan Ghosh SEED Grant Generation of forebrain neurons from human embryonic stem cells $612,075
Total:
$158,572,494.00

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