Summaries of Review for Applications to RFA 09-03
Review Summaries for RFA 09-03: CIRM Stem Cell Transplantation Immunology Awards
The following is a listing of all applications reviewed under RFA 09-03 for CIRM Stem Cell Transplantation Immunology Awards. Applications include the score (between 0 and 100, with 100 being the best) and a funding recommendation (indicated by the color key below) made by the Grants Working Group (GWG). A link to the Public Abstract (provided by applicant), Statement of Benefit to California (provided by applicant), and Public Review Report are available for each application by clicking on the respective application number.
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= Recommended for funding |
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= Not Recommended for funding at this time |
| Application Number | ICOC Decision | Title | Scientific Score |
|---|---|---|---|
| RM1-01725 | Approved | Regulatory T cell induced tolerance to ESC transplantation | 87 |
| RM1-01730 | Approved | Inactivating NK cell reactivity to facilitate transplantation of stem cell derived tissue | 84 |
| RM1-01703 | Approved | Stem cell tolerance through the use of engineered antigen-specific regulatory T cells | 81 |
| RM1-01702 | Approved | Stem cell differentiation to thymic epithelium for inducing tolerance to stem cells | 81 |
| RM1-01720 | Approved | Induction of immune tolerance after spinal grafting of human ES-derived neural precursors | 80 |
| RM1-01729 | Approved | Generation of regulatory T cells by reprogramming | 80 |
| RM1-01739 | Approved | Engineered immune tolerance by Stem Cell-derived thymic regeneration | 73 |
| RM1-01735 | Approved | Role of HLA in neural stem cell rejection using humanized mice | 73 |
| RM1-01706 | Approved | Engineering Embryonic Stem Cell Allografts for Operational Tolerance | 72 |
| RM1-01711 | Approved | Development of an immune tolerant hESC source for allogeneic cell therapy applications | 72 |
| RM1-01707 | Approved | Engineering Thymic Regeneration to Induce Tolerance | 70 |
| RM1-01709 | Approved | Role of Innate Immunity in hematopoeitic stem cell-mediated allograft tolerance | 70 |
| RM1-01732 | Approved | Human Immune System Mouse models as preclinical platforms for stem cell derived grafts | 70 |
| RM1-01718 | Approved | Maternal and Fetal Immune Responses to In Utero Hematopoietic Stem Cell Transplantation | 69 |
| RM1-01724 | Approved | Donor natural killer (NK) cells as "veto" cells to promote donor-specific tolerance | 69 |
| RM1-01743 | Approved | Induction of immune tolerance to human embryonic stem cell-derived allografts | 68 |
| RM1-01717 | Approved | Thymus based tolerance to stem cell therapies | 67 |
| RM1-01745 | -- | Immune tolerance induction for islet graft in pancreas of autoimmune diabetic recipient | 67 |
| RM1-01710 | Approved | Application of Tolerogenic Dendritic Cells for Hematopoietic Stem Cell Transplantation | 66 |
| RM1-01705 | -- | Immune Tolerance by ES-cell Derived Dendritic Cells | 65 |
| RM1-01733 | Approved | Purified allogeneic hematopoietic stem cells as a platform for tolerance induction | 65 |
| RM1-01740 | -- | Enhancing Stem Cell Transplant Survival in the CNS | 64 |
| RM1-01721 | -- | Innate and Adaptive Immunity to Stem Cell Allografts: Pathways to Tolerance Induction | 64 |
| RM1-01731 | -- | Characterizing the Alloimmune Response to Human ES-derived Pancreatic Lineage Cells | 63 |
| RM1-01744 | -- | TERT as immunological barrier to iPS derivatives transplantation | 62 |
| RM1-01728 | -- | Tolerance to stem cell grafts | 62 |
| RM1-01742 | -- | Understanding Immunobiology of Human Induced Pluripotent Stem Cells | -- |
| RM1-01738 | -- | Prevention of stem cell transplant allorejection through DRAK2 blockade | -- |
| RM1-01722 | -- | Tolerance induction using fetal multilineage hematopoietic stem cells | -- |
| RM1-01716 | -- | Immune modulation to improve stem cell engraftment | -- |
| RM1-01712 | -- | Activated Natural Killer cells for cancer immunotherapy and stem cell transplantation. | -- |
| RM1-01714 | -- | Immune Tolerance to Stem Cells in Liver Transplant Regeneration and Survival | -- |
| RM1-01737 | -- | Inducing transplantation tolerance with MSCs | -- |
| RM1-01726 | -- | iPSC-Derived T Cells for the Prevention of Autoimmune Pulmonary Hypertension | -- |
| RM1-01713 | -- | hESC-Derivates Suppress Host Inflammation | -- |
| RM1-01723 | -- | Comparative profiling of the immune response following grafting in the CNS | -- |
| RM1-01719 | -- | Analysis of Immunogenicity of Human iPS-Derived Hematopoietic Progenitors | -- |
| RM1-01727 | -- | Immunosuppressive Pericytes as Transplantable Natural Ancestors of Mesenchymal Stem Cells | -- |
| RM1-01746 | -- | Transplantation of human pluripotent stem cells into a bone defect made in humanized mice | -- |
| RM1-01741 | -- | Alloimmunogenicity and Tolerogenic Acceptance of ESC-Derived Hepatopancreatic Cells | -- |
| RM1-01704 | -- | Enhancing stem cell tolerance by activating adenosine A2A receptors | -- |
| RM1-01736 | -- | Immunogenicity of HLA-homozygous human parthenogenetic stem cells | -- |
| RM1-01701 | -- | Tolerance Induction by Mixed Allogeneic and Autologous Bone Marrow Transplantation. | -- |
| RM1-01715 | -- | Stem Cell Transplantation using Psoralen treated T-lymphocytes | -- |
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